Conference Proceeding

Pediatric inflammatory myofibroblastic tumors of larynx: two case reports varying clinical presentation

Dr.Jaichandrika,
Kanchi Kamakoti Childs trust hospital, Chennai, Tamilnadu, India

Inflammatory myo-fibroblastic tumor (IMFT) is a rare tumor of intermediate malignant potential.

Dr. Jaichandrika Completed M.B.B.S in the year 2013 from meenakshi medical college and research institute, Kanchipuram. Later she started Working as resident at Apollo first medicine in pediatric department. Presently she is working as a junior resident in pediatric oncology kanchi kamakoti child's trust hospital, India.

Introduction: Inflammatory myo-fibroblastic tumor (IMFT) is a rare tumor of intermediate malignant potential. It may occur in a wide range of anatomical locations. One-third is found in the respiratory tract. We report two Cases with IMFT of airway at our institution.
Case Report: CASE1: A 6yr old male child presented with hoarseness of voice. On evaluation, a polypoid nodule was noted in right vocal cord which was excised through end laryngeal route. Histopathology was suggestive of ALK negative IMFT. He presented with recurrence after 4months for which he underwent endolaryngeal rescission and was started on celecoxib. He is under follow up with Celecoxib, in remission.
CASE2: 7yrs old male child presented with cough and respiratory distress. Bronchoscopy and HRCT showed a polypoidal lesion with calcification arising from left anterior lateral wall of trachea with significant narrowing of the lesion. Biographypsy of the mass confirmed the inflammatory fibroblastic tumor.
Discussion: IMFT indicates a proliferative myo-fibroblastic growth. Surgical resection should be recommended for all lesions if not prohibited by anatomic location or morbidity. Patients should be followed up closely for recurrence .In most cases, complete surgical excision suffice. However recurrences can be managed with chemotherapy.
Conclusion: These two cases highlight the importance of multidisplinary approach in rare tumors in difficult anatomical locations. Complete surgical excision remains the treatment of choice and chemotherapy is reserved for recurrences.

Published: 12 May 2017