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The Infrared Absorption of Protein Molecules with α- helix Conformation and its Properties

Original Research Article

Authors:

In order to investigate the relationship of molecular structure of protein molecules with its functions, The experimental results show that there is a new band of 1650cm-1 close to the conventional amide-I band


Published: 03 Mar 2017

Capillary Zone Electrophoresis-electrospray Ionization-mass Spectrometry is Ready for Large-scale Proteomics

Review Article

Authors:

Capillary zone electrophoresis-electrospray ionization-tandem mass spectrometry (CZE-ESI-MS/MS) has re-attracted great attentions for large-scale proteomics. The state-of-the-art CZE-MS/MS can routinely approach micro-liter scale loading capacity,


Published: 25 May 2017

The Canonical Correlation of Biomarkers in Relation to the Concentration of 37 Fatty Acids of Erythrocyte Membranes after Coronary Stent Implantation

Original Research Article

Authors:

The treatment of significant stenosis of coronary arteries by percutaneous coronary intervention (PCI) with stent implantation elicits an inflammatory response. This study was aimed at evaluating the relationship between the fatty acid profile of erythrocyte membranes and ...


Published: 16 Aug 2017

Application of Infrared Probe Technique to Structural Analysis of Amyloid Fibril

Editorial Article

Authors:

Amyloid formation is an abnormal protein aggregation process, through which the aggregated proteins form a unique type of fibrillar aggregates termed as amyloid fibril [1]. The basic structural unit of amyloid fibril is composed of two interdigitated beta sheets.


Published: 19 May 2017

Small Molecule Drugs Development: Where to Go?

Editorial Article

Authors:

In recent years, the drug discovery success has been driven mainly by biologics, which currently represent a sizable portion of the top-selling drugs. The advantages including oral availability, relatively easy to make, scalability, and low cost make small molecule drugs still indispensable for human health and well-being.


Published: 14 Apr 2017

Perspectives on methods development for oxidative stress biomarkers quantification

Editorial Article

Authors:

Oxidative stress is defined as an imbalance of antioxidants and oxidants in favour of the latter, potentially leading to damage and disruption of redox signalling and/or control of molecular damage (Jones, 2006; Sies, 2015).


Published: 08 Apr 2017

Organic synthesis and chemical analysis

Editorial Article

Authors:

Chemical analysis is very important in many sciences. On reflection, we also realize that it constitutes a cornerstone in our lives and societies as well. This will not only be beneficial for scientists in many disciplines; it will also make it possible to manage the use of chemicals in industry.


Published: 27 Mar 2017

Importance and Challenges of Instrumental Analysis in Drug Development

Editorial Article

Authors:

Demand for instrumental analysis in pharmaceutical industry is soaring in recent years [1]. Among the instrumental analytical methods used in the whole drug development process, the analysis using chromatographic analysis techniques is the most widely used one [2,3].


Published: 10 Aug 2017

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